Cosolute and Crowding Effects on a Side-By-Side Protein Dimer

Side Effects of Shot Peening on Fatigue Crack Initiation Life

Shot peening beneficial effects on fatigue life of mechanical components are well known. However, there are some reports in the literature that indicate inappropriate shot peening parameters tend to reduce the fatigue life. It is therefore, the purpose of this study to find a logical quantitative justification for these observations. Using finite element method, a dynamic elastic-plastic simula...

Comparing supply side and demand side options for electrifying a local area using life cycle analysis of energy technologies and demand side programs

The main aim of this paper is to select the best portfolio of renewable energy technologies (RETs) for electrifying an elected area which is not connected to any other grids. Minimizing total costs of the system is considered as the main factor in finding the best decision. In order to make the optimum plan more applicable, the technique of life cycle analysis is applied. This technique takes i...

Side Effects

Side Effects

This section covers basic topics and illustrates the technical notion of a computational effect with several mathematical and programming examples. In everyday language, a “side effect” refers to the unintended or unforeseen consequences of an action. By analogy, in order to identify the side effect of a given computation, it is first necessary to isolate the “publicly stated” or “publicly expe...

Crowding Alone Cannot Account for Cosolute Effect on Amyloid Aggregation

Amyloid fiber formation is a specific form of protein aggregation, often resulting from the misfolding of native proteins. Aimed at modeling the crowded environment of the cell, recent experiments showed a reduction in fibrillation halftimes for amyloid-forming peptides in the presence of cosolutes that are preferentially excluded from proteins and peptides. The effect of excluded cosolutes has...